New Heterobimetallic Complexes with Anticancer Activity
The modification of ferrociphenol by appending a phosphine moiety to the cyclopentadienyl ring (initially unsubstituted) of the ferrocene unit offers a new and promising approach to enhancing this anticancer agent and enables the synthesis of novel biologically active derivatives.
New Molecular Daisy Chain Architectures
What insights can we get from a daisy chain structure without a preferential low-energy arrangement of mechanically linked components?
Gene-modified Spider Creates Red Fluorescent Silk
CRISPR-Cas9 was used to edit spider genes, revealing their roles in eye development and enabling fluorescent silk production for the first time.
Safe & Fast Flow Synthesis of Nitrofuran Pharmaceuticals
Automated continuous flow synthesis enables rapid nitration of furfural to produce nitrofuran-based pharmaceuticals with high yields in five minutes.
Aqueous Micellar Catalysis Enhances (Hetero)Aryl Halide Dehalogenation
A nickel-catalyzed method for the hydro- and deuterodehalogenation of (hetero)aryl halides under aqueous micellar conditions achieves high efficiency and excellent yields in over 40 examples.
Engineered Gold–Iron Nanoclusters for Enhanced Tumor Therapy
Au₈Fe₂ nanoclusters activate multiple tumor cell death pathways and enable MRI-based diagnosis
Lessons from the Iberian Outage: Chemistry Must Be Resilient, Not Just Sustainable
Ten principles want to encourage dialogue and research into how chemistry can withstand energy volatility, resource limitations, and geopolitical instability
Do You Know ChemSec’s SIN List and How You Could Use It?
The SIN (Substitute It Now) List, developed by the non-profit organization ChemSec, identifies hazardous chemicals that are likely to be banned or restricted under EU chemicals legislation such as REACH
Will There Still Be Chocolate in the Future?
Challenges and biotechnological solutions for chocolate production
The Chemistry of the Smoke That Signals the Decision of the Papal Conclave
The smoke that signals the decision—white for success, black for no decision—is controlled by some interesting chemistry
Structural Stability and Water Permeability of h-BN Membranes
Analyzing the behavior of pores within a freestanding hexagonal boron nitride (h-BN) monolayer in contact with water molecules
Luis Oro Honored with Spain’s Oldest Scientific Award
Medalla Echegaray 2024 recognizes Luis Oro’s distinguished research career
Where Do Parrots Get Their Colors?
Unlike other birds, parrots create their own colors—thanks to special pigments and nanoscale feather designs
Transmutation of a Metallabenzene for Pyridine Synthesis
Fluorescent pyridine phosphonium salts via transmutation of metallabenzenes
Air-Stable Ligand-Free Nickel Anion
A Tb₂Ni lanthanide–nickelide cluster featuring a ligand-free Ni²⁻ anion has been synthesized and stabilized inside a fullerene cage
Scalable and Flexible Synthesis of Spirotetrahydroquinoline Derivatives
Efficient and practical copper-catalyzed method for the synthesis of spirotetrahydroquinoline (STHQ) derivatives
Light-Driven Routes to Strained Borylated Rings
Energy transfer catalysis under visible light to construct borylated cyclopropane and cyclobutane rings
Room-Temperature C(sp³)–C(sp²) Bond Formation from Alcohols and Aryl Acids
This method unites two activation modes to streamline access to aryl–alkyl products from abundant feedstocks
Mild Aqueous Synthesis of Thioamides
Chemoselective thioamidation of potassium acyltrifluoroborates (KATs) and amines using elemental sulfur in aqueous solution