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Enantioselective Total Synthesis of the Natural Product (+)-Punctaporonin U
A concise synthetic strategy combines rare cascade reactions to construct the complex, biologically active sesquiterpene (+)-punctaporonin U
Editors’ Choice: Daily Highlights from Chemistry Europe Journals
Selection of just published articles from Chemistry Europe, GDCh, and ACES journals

Breaking the NIR-IIx Barrier: Organic Small-Molecule Fluorophores for Deep-Tissue Imaging
Researchers develop bright, stable organic dyes that enable precise deep-tissue imaging and disease detection in the NIR-IIx spectrum

Supramolecular Nanocomplex Overcomes Drug-Resistant Liver Cancer by Inducing Dual-Site Ferroptosis
A natural nanocomplex overcomes drug resistance in liver cancer by inducing ferroptosis through a three-part mechanism that reduces glutathione in cancer cells, weakening their antioxidant defenses and causing cell death

Hybrid Hydrogels for Water Purification And Drug Synthesis
Dual-action Fmoc hydrogels remove toxic p-nitrophenol and show antibacterial activity, advancing eco-friendly water purification and green synthesis

Light And Heat-Responsive Self-Healing Smart Gel System
A simple gel made from surfactants and an ionic liquid shows a UV-triggered gel-to-liquid change, reversible thermal response, and rapid self-healing