Andres Jäschke, University of Heidelberg, Germany, has received the Albrecht Kossel Award 2022 from the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society). The award honors researchers who have done excellent work in the field of biochemistry. It was presented at the conference of the GDCh Division of Biochemistry in Münster, Germany, on June 30, 2022.
Professor Jäschke is honored for his pioneering contributions to the catalysis, regulation, modification, and imaging of RNA.
Andres Jäschke studied chemistry at Humboldt University, Berlin, Germany, where he received his Ph.D. in 1993 under the supervision of Dieter Cech. He then worked as a Postdoctoral Fellow at the Massachusetts Institute of Technology (MIT), Cambridge, USA, with Alexander Rich.
From 1995 to 2002, Jäschke served as group leader at the Institute of Chemistry at Free University Berlin, Germany. He completed his habilitation in bioorganic chemistry there in 2000. In 2002, he was named Full Professor of Pharmaceutical Chemistry and Director at the Institute of Pharmacy and Molecular Biotechnology at the University of Heidelberg.
Among other honors, Jäschke received the BioFuture Award of the German Federal Ministry of Education and Research (BMBF) in 1998 and an ERC Advanced Grant in 2020.
Selected Publications
- A DNA-Based Two-Component Excitonic Switch Utilizing High-Performance Diarylethenes,
Simon M. Büllmann, Theresa Kolmar, Nicolas F. Zorn, Jana Zaumseil, Andres Jäschke,
Angew. Chem. Int. Ed. 2022.
https://doi.org/10.1002/anie.202117735 - Exploring the energy landscape of a SAM-I riboswitch,
Christoph Manz, Andrei Yu Kobitski, Ayan Samanta, Karin Nienhaus, Andres Jäschke, Gerd Ulrich Nienhaus,
J. Biol. Phys. 2021, 47, 371–386.
https://doi.org/10.1007/s10867-021-09584-7 - Development of Red-Shifted and Fluorogenic Nucleoside and Oligonucleotide Diarylethene Photoswitches,
Theresa Kolmar, Antonia Becker, Ronja A. Pfretzschner, Alina Lelke, Andres Jäschke,
Chem. Eur. J. 2021, 27, 17386–17394.
https://doi.org/10.1002/chem.202103133 - NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs,
Hana Cahová, Marie-Luise Winz, Katharina Höfer, Gabriele Nübel, Andres Jäschke,
Nature 2014, 519, 374–377.
https://doi.org/10.1038/nature14020 - APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP,
Sascha W. Weyer, Maja Klevanski, Andrea Delekate, Vootele Voikar, Dorothee Aydin, Meike Hick, Mikhail Filippov, Natalia Drost, Kristin L. Schaller, Martina Saar, Miriam A. Vogt, Peter Gass, Ayan Samanta, Andres Jäschke, Martin Korte, David P. Wolfer, John H. Caldwell, Ulrike C. Müller,
EMBO J. 2011, 30, 2266–2280.
https://doi.org/10.1038/emboj.2011.119 - Post-Synthetic Modification of DNA by Inverse-Electron-Demand Diels−Alder Reaction,
Juliane Schoch, Manfred Wiessler, Andres Jäschke,
J. Am. Chem. Soc. 2010, 132, 8846–8847.
https://doi.org/10.1021/ja102871p
