New light-activated prodrug designed for combining photodynamic therapy with a traditional cytotoxic agent
Author Archive for: Adrian Neal (17)
Structural Insights into Sleep Regulation
Crystal structures of orexin receptors reveal new information on their activation by small-molecule ligands
Fighting Drug Resistance in Bacteria
Could naphthalimide-imidazole conjugates lead to the next generation of antibiotics against MRSA?
Diagnosis by Lab-on-a-Drone
In the future, drones equipped with PCR instruments and smartphones could be flying over disease-stricken areas
Squeeze a Cell to See It
Microfluidic squeezing of living cells allows intracellular specific labeling and visualization of proteins
Fluorophores Moonlighting as Antibiotics
A BODIPY fluorescent dye with antibiotic activity against drug-resistant bacteria
Death by Peroxide for Cancer Cells
Five-membered ring organic peroxide is cytotoxic to cancer cells by ferroptosis, not apoptosis
Answering Nature’s Call with a Drug
Medicinal chemists develop a new lead candidate against overactive bladder
Proteins Modified to Order
A new method for site-selective protein conjugation based on aromatic nucleophilic substitution
Identifying Bacterial Biofilms
A fluorescent probe for monitoring biofilms in clinical situations has been discovered