An enantioselective route to form epoxides by using kinetic resolution techniques has been developed
Author Archive for: Vikki Cantrill (39)
Discerning Imine Hydrogenation
A new method to selectively hydrogenate imine bonds by using an iridium complex has been developed
Squaring Up To Michael Additions
Organocatalytic continuous-flow Michael additions give great selectivity and good product diversity
Chiral Column? Here’s One I Made Earlier
Continuous-flow Diels–Alder reactions with a homemade HPLC column give good selectivity for >150 h
Angling for a Route to Fish Proteins
The chemical synthesis of a masked analogue of a fish antifreeze protein has been developed
Organolithium Cross-Coupling
Practical method for the fast and highly selective direct cross-coupling of organolithium reagents has been developed
Targeting Cholera Toxin
The synthesis and initial biological evaluation of a calixarene-based inhibitor for cholera toxin has been developed
Cryptophane Proves Good Host
A strategy for the easy synthesis of a water-soluble cryptophane-111 derivative has been developed
Hope for Hepatitis Drug
A straightforward synthesis of an antiviral drug, entecavir, to treat hepatitis B has industrial scale-up potential
Proper Path to Propiolic Acids
A versatile synthesis of various propiolic acid derivatives by using cesium fluoride has been developed