The modification of ferrociphenol by appending a phosphine moiety to the cyclopentadienyl ring (initially unsubstituted) of the ferrocene unit offers a new and promising approach to enhancing this anticancer agent and enables the synthesis of novel biologically active derivatives.

What insights can we get from a daisy chain structure without a preferential low-energy arrangement of mechanically linked components?

CRISPR-Cas9 was used to edit spider genes, revealing their roles in eye development and enabling fluorescent silk production for the first time.

Automated continuous flow synthesis enables rapid nitration of furfural to produce nitrofuran-based pharmaceuticals with high yields in five minutes.

A nickel-catalyzed method for the hydro- and deuterodehalogenation of (hetero)aryl halides under aqueous micellar conditions achieves high efficiency and excellent yields in over 40 examples.

Au₈Fe₂ nanoclusters activate multiple tumor cell death pathways and enable MRI-based diagnosis

Ten principles want to encourage dialogue and research into how chemistry can withstand energy volatility, resource limitations, and geopolitical instability

The SIN (Substitute It Now) List, developed by the non-profit organization ChemSec, identifies hazardous chemicals that are likely to be banned or restricted under EU chemicals legislation such as REACH

Challenges and biotechnological solutions for chocolate production

The smoke that signals the decision—white for success, black for no decision—is controlled by some interesting chemistry