A mild, efficient system for selectively deprotecting and modifying N-heterocycles in a single step

Method Simplifies Deprotection and Modification of N-Heterocycles

BioMed X Launches Call to Support U.S. Scientists Facing NIH Funding Loss
BioMed X Institute opens its global crowdsourcing platform to help principal investigators in biomedical research who have lost their NIH funding to find alternative project sponsors among the global pharmaceutical industry

4th Employment Survey for European Chemists Now Open
The survey is conducted by EuChemS and the European Young Chemists’ Network (EYCN), supported by Chemistry Europe, the Royal Society of Chemistry (RSC), and the American Chemical Society (ACS)

Rapid Synthesis of 5-Amino-4-Cyanoxazoles in a Ball Mill
Mechanochemistry enables a rapid, solvent-free synthesis of 5-amino-4-cyanoxazoles in just 10 minutes, achieving high yields with minimal waste

Sandmeyer Prize 2025
The Swiss Chemical Society (SCS) awards the F. Hoffmann-La Roche team involved in the commercial manufacturing process of Divarasib, an KRAS G12C inhibitor for cancer treatment

Enhance Product Safety with AI and Web 3.0 Technologies
Merck and Zebra collaborate to address challenges around product verification, authenticity, and trust

Exploring New Fragrance Frontiers
Exploring cage bicyclic hydrocarbons as bioisosteres for novel fragrances

Superoxide-Driven Catalyst in Ergot Alkaloid Biosynthesis
A previously unobserved enzymatic strategy that expands the understanding of metalloenzyme catalysis and may guide the design of new biocatalysts for pharmaceutical synthesis

Nominations Open for the Primo Levi Award
The Primo Levi Award honors chemists who advance human rights, ethical responsibility, and the societal role of chemistry

Cyclo-P₅⁻ Revisited: Solid-State Characterization
Stabilization of the cyclo-P₅⁻ anion in the solid state through complexation of the alkaline metal cation with [2.2.2]cryptand, providing the first crystallographic characterization and detailed spectroscopic analysis