Novel 19-substituted benzoquinone ansamycins inhibit heat shock protein 90 without causing toxic effects in vitro
Preventing Geldanamycin’s Toxicity
Long Wavelength Fluorescein Analogues
Modification of fluorescene leads to analogues with better photo-physical characteristics
Lactimidomycin – No Effect on Cell Motility but Still Cytotoxic
Synthesis and biological re-evaluation of the cytotoxic effects of Lactimidomycin and its progeny in cancer cells
Assisting C−H Activation
Detailed study into the mechanism for carboxylate-assisted C−H bond activation at Pd(IV) centers has been undertaken
Magnetic Catalytic Recycling
A magnetic can be used to recycle catalytic nanoparticles that could be used for an important and widely used set of reactions
Green Oxidations on Graphene
Graphene as an aerobic oxidation carbocatalyst derived from natural resources
Machine-Assisted Flow Synthesis
Flow-based syntheses to accelerate multistep routes to highly complex, medically relevant compounds have been evaluated
Novel Therapeutic Target for Pancreatic Cancer
A non-canonical metabolism of the amino acid glutamine sustains pancreatic ductal adenocarcinoma’s growth
Most Accessed Articles: March 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for March 2013
Novel Anti-influenza Drugs
Difluorosialic derivatives are a novel class of anti-influenza medicaments acting against drug-resistant viral strains