Various polyhedral boranes are the subject of significant attention because of their various useful properties and important applications such as in boron neutron-capture cancer therapy.
Vadim Kukushkin, Nadezhda Bokach, Saint Petersburg State University, Russia, and co-workers found an efficient route for facile functionalization of decaborates that can be achieved through a novel reaction between closo-decaborate clusters bearing the C≡N group and azomethine ylides. This selectively affords products of the nucleophilic addition viz., the borylated enamino ketones.
The observed reaction represents the first example of addition of any C-nucleophiles to nitrilium derivatives of boron clusters.
In addition the reaction mechanism has been studied by density functional calculations.
- Coupling of Azomethine Ylides with Nitrilium Derivatives of closo-Decaborate Clusters: A Synthetic and Theoretical Study,
Aleksey L. Mindich, Nadezhda A. Bokach, Maxim L. Kuznetsov, Matti Haukka, Andrey P. Zhdanov, Konstantin Yu. Zhizhin, Serguei A. Miltsov, Nikolay T. Kuznetsov, Vadim Yu. Kukushkin,