In this issue, R. Zenobi et al. review chemical imaging on the nanoscale by means of tip-enhanced Raman spectroscopy. What are the benefits, shortcomings, and pitfalls of this technique? In a Minireview, M. A. Tasdelen and Y. Yagci discuss light-induced click reactions. G. Frenking and M. Herrmann object to the idea of quadruply bonded C2 brought forward by R. Hoffmann et al. in a trialogue in Issue 10; the latter reject the criticism, and add new arguments. The Highlight deals with C–C and C–N bond formation catalyzed by copper and mediated by light (A. Jacobi von Wendelin).
In the Communications section, R. Pini et al. present photothermally activated hybrid films for the confined release of chemicals. U. Häussermann et al. report on LiBSi2, an open tetrahedral framework structure. L. T. Maillard et al. describe the synthesis and structure of helical oligomers of thiazole-based γ-amino acids. Q.-L. Zhou et al. succeeded in the iridium-catalyzed enantioselective hydrogenation of unsaturated heterocyclic acids.