In this issue’s Review, A. J. Bissette and S. P. Fletcher discuss self-replication and autocatalysis in biological processes. Which reactions have prebiotic relevance? In a Minireview, J. Suffert et al. write about fenestranes in synthesis. The Highlights deal with the geometry of single-molecule magnets (M. Dey and N. Gogoi) and structures of GPCRs (F. Hausch).
In the Communications section, H. Ito et al. reveal how to control mechano- and seeding-triggered single-crystal phase transitions of gold(I) complexes (see picture). K. Seppelt et al. observed the release of xenon when XeF2/F− acceptors act as one-electron oxidants. K. D. Moeller et al. succeeded in controlling the course of a radical cation-derived oxidative cyclization reaction. M. Shiramizu and F. D. Toste expand the scope of biomass-derived chemicals through tandem reactions based on oxorhenium-catalyzed deoxydehydration.