Irwin Rose (1926 – 2015)

Irwin Rose (1926 – 2015)

Author: ChemViews (Photo: Ⓒ University of Chicago)

Irwin Rose, one of the 2004 Nobel Laureates in Chemistry, has passed away on June 2.

Rose received the Nobel Prize together with Aaron Ciechanover and Avram Hershko for the discovery of ubiquitin-mediated protein degradation. Ubiquitin (ubiquitous immunopoietic polypeptide) is a small protein that can be attached to other proteins and marks them for breakdown by the proteasome.

Irwin Rose
attended Washington State University, Pullman, WA, USA, and the University of Chicago, IL, USA, where he received his bachelor’s degree in 1948 and his Ph.D. in biochemistry in 1952. He joined the Yale School of Medicine, New Haven, CT, USA, as Instructor in Biochemistry in 1954. From 1963, he worked in basic research at the Institute for Cancer Research of the Fox Chase Cancer Center, Philadelphia, PA, USA, and stayed there until he retired in 1995.

Selected Publications


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