In this week’s Review, S. Quideau et al. discuss the chemical properties, biological activity, and synthesis of plant polyphenols. How do these natural products serve plants as a defense and chemists as an inspiration in drug development? The Highlights deal with nanocrystal self-assembly by oriented attachment, hydrogen storage in highly porous metal-organic frameworks, and a genome-wide correlation between mRNA and proteins in a single cell.
In the Communications section, K. Cai et al. report on redox-responsive nanoreservoirs based on silica and collagen for targeted drug delivery. S. Blechert et al. show how to oxidize amines to imines in a metal-free aerobic one-pot reaction. P. Izak et al. present a procedure for the separation of CO2 and impurities from biogas by means of a condensing-liquid membrane (see picture). A. I. Cooper et al. succeeded in the synthesis of a molecular organic solid in which microporosity can be switched on and off.