Quick Test for Stem Cells

Quick Test for Stem Cells

Author: ChemistryViews

Pluripotent stem cells—which have the potential to mature into any cell in the body—are being widely studied for their role in treating a vast array of human diseases and for generating cells and tissues for transplantation. The test to see whether a cell line is pluripotent can take up to eight weeks and requires animal testing.

Jeanne Loring and co-workers, Scripps Research Institute, USA, have developed a new diagnostic test, PluriTest, which uses microarray technology. This enables the simultaneous analysis of thousands of different DNA sequences. Users can upload raw data from a microarray analysis to the PluriTest website. Comparison with a database created by the team, which contains molecular models of normal human embryonic and induced pluripotent stem cells, identifies whether a cell line is pluripotent in 10 minutes.

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