Ageless Proteins

  • Author: David Bradley
  • Published: 28 February 2012
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
  • Source / Publisher: Nature/Nature Publishing Group
thumbnail image: Ageless Proteins

The sirtuins proteins have been referred to colloquially as "longevity" proteins. They are highly conserved enzymes, deacetylases, that have been demonstrated to influence the lifespan of yeast, nematode worms and fruitflies, the common laboratory subjects of the molecular biology laboratory.

In the last few decades understanding their function has stimulated interest in how they might be modulated in humans to perhaps increase the healthy human lifespan. Researchers at the Bar-Ilan University, Israel, and their colleagues have demonstrated that SIRT6 regulates the lifespan of male mice, which brings us tantalisingly close to therapeutic implications for humans.

Article Views: 1894

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

Bookmark and Share

If you would like to reuse any content, in print or online, from, please contact us first for permission. more

CONNECT: on Facebook on Twitter on YouTube on LinkedIn Sign up for our free newsletter

Magazine of Chemistry Europe (16 European Chemical Societies)published by Wiley-VCH