A Labor of Love

A Labor of Love

Author: David Bradley

US researchers have worked studiously to discover that microRNAs could have the potential to prevent pre-term births.

In tests with pregnant mice as well as human uterine tissue, the researchers have revealed a feedback cycle involving microRNAs, two proteins, ZEB1 and ZEB2, and the pregnancy hormone progesterone. Specifically, they found that miR-200s
block the expression of ZEB 1 and 2 at least until progesterone levels fall and uterine contractions and labor can begin.

The hope is that controlling the microRNAs might allow this switch to be delayed regardless of progesterone levels.


Leave a Reply

Your email address will not be published.