The number of effective anti-tuberculosis (TB) drugs continues to dwindle; can we find new agents for treating drug-resistant TB?

A Drug Pipeline Going Dry

Aluminium and Zirconium in Synergy
Fine-tuning of catalytic activity is possible with bimetallic mesoporous materials containing aluminum and zirconium

Chemical Intermediate from Biomass-derived Carbohydrate
Direct catalytic synthesis of 5-methylfurfural (MF) - an important chemical intermediate - from biomass-derived carbohydrates

Protein Discrimination in Human Blood
Synthetic polypeptide conjugate that selectively binds target proteins could offer alternative to antibodies for protein recognition

Hydrogen Adsorption on MOFs
MOFs for H2 storage still have a long way to go – as new experiments considering entropic contribution to adsorption energy show

Bio-Based Platform Chemicals
Recent developments in the biotechnological production of hydrocarbons are paving the way for bio-based platform chemicals

New Finding for Belousov–Zhabotinsky
First measurements of cross-diffusion coefficients for a five-component system – the Belousov–Zhabotinsky reaction

Water-Soluble Iridium Biosensors
Sugar containing iridium complexes shown to be water-soluble, biocompatible and suitable for lectin sensing

New Routes to IN Inhibition
HIV-1 integrase (IN) is an essential enzyme for HIV-1 replication: New routes to IN inhibition could overcome drug resistance

Hydrogenase Cofactor Simply Synthesized
New route to hydrogenase cofactor azadithiolate provides a simple way to make model enzymes for H2 fuel production