Cyclohexane-1,2-dione hydrolase accepts a wider range of substrates than other thiamine diphosphate dependent enzymes

Scoping Out the Competition

Gold Medal for Levitt and Warshel
Michael Levitt and Arieh Warshel, both USA, receive the highest recognition of the Israel Chemical Society

Angewandte Chemie 4/2014: High Stability
Overview of the latest issue of Angewandte Chemie

Hunt for the Killer Bug
Identification of living Legionella by using specific metabolic lipopolysaccharides

Silenced
Overcoming multidrug resistance in cancer cells by silencing genes with RNA

A New Approach to Malaria Treatment?
Halogenated natural alkaloids show herbicidal and antiplasmodial activity

Fungal Morphology Matters
Morphological engineering techniques are used to improve the production of metabolites by filamentous fungi

A New Class of Anti-AIDS Drugs?
By blocking HIV-mediated destruction of immune cells, the caspase 1 inhibitor VX-765 shows promise as a new AIDS therapy

Sequence-Specific DNA Alkylation
DNA alkylation targeting for Kras codon 13 mutation may be a promising approach to overcome the problem of drug-resistance

Active Microfluidic Paper Chip
A full range of fluidic operations can be achieved with active, paper-based microfluidic chips driven by electrowetting