By metabolizing L-carnitine, a nutrient abundant in red meat, intestinal bacteria promote atherosclerosis

Meat, Bacteria, and Atherosclerosis

Exploiting Structural Differences in Serotonin Receptors
Serotonin receptors present structural differences which can be used to design agonistic drugs devoid of side effects

Hope for Hepatitis Drug
A straightforward synthesis of an antiviral drug, entecavir, to treat hepatitis B has industrial scale-up potential

New Route to Anticancer Agent Quinocarcin
Synthesis of quinocarcin through a convergent strategy based on Sonogashira coupling and gold(I)-catalyzed hydroamination

Awakening to New Drugs against Sleeping Sickness
Structure–activity relationships and optimization of triazine nitriles as rhodesain inhibitors

Intellectual Freedom in Academic Scientific Research under Threat
Sir John Meurig Thomas, UK, argues that scientific research motivated by intellectual curiosity is being restricted by funding bodies

Magnetic Nanoparticles Detect Pathogens
A novel iron oxide nanoparticle-based system detects pathogens with high sensitivity, specificity, and rapidity

Silencing a Tumorigenic Catalyst
Novel isocitrate dehydrogenases 1 and 2 inhibitors prevent the growth of brain and blood tumors

Nanomachine Drug Delivery
A sensing–actuating nanomachine based on Janus Au–mesoporous silica nanoparticles for enzyme-controlled cargo release

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