US scientists revealed that the sirtuin SIRT6 is not a deacetylase but a long-chain fatty-acyl hydrolase

Acetyl or Myristoyl: That is the Question

DNA Logic Gates for Metal-ion Sensing
Electronic logic gates made from DNA in conjunction with metal-ion sensing could be used for point-of-care sensing devices

Preventing Geldanamycin’s Toxicity
Novel 19-substituted benzoquinone ansamycins inhibit heat shock protein 90 without causing toxic effects in vitro

9th European Congress of Chemical Engineering (ECCE)
Europe’s largest science and business congress on Chemical Engineering and Applied Biotechnology was held in Den Haag

Long Wavelength Fluorescein Analogues
Modification of fluorescene leads to analogues with better photo-physical characteristics

Lactimidomycin – No Effect on Cell Motility but Still Cytotoxic
Synthesis and biological re-evaluation of the cytotoxic effects of Lactimidomycin and its progeny in cancer cells

Novel Therapeutic Target for Pancreatic Cancer
A non-canonical metabolism of the amino acid glutamine sustains pancreatic ductal adenocarcinoma’s growth

Most Accessed Articles: March 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for March 2013

Novel Anti-influenza Drugs
Difluorosialic derivatives are a novel class of anti-influenza medicaments acting against drug-resistant viral strains

Threaded through a Pore
Single-molecule detection of hydroxymethylcytosine in DNA by threading DNA through a membrane-embedded protein pore