Tunable, pH-responsive nanoparticles can be selectively activated in different endocytic compartments

Endocytic-Targeting, pH-Responsive Nanoparticles

Single Peptide-Surface Interaction
Investigations into how peptides bind to surfaces show that weak, non-covalent interactions may be the key to new biomimetic materials

Dopamine Testing on the Move
Fast-scan cyclic voltammetry with carbon-fiber microelectrodes can probe neurochemical signaling in freely moving rats

DNA Origami
Miniature architectural forms—including a round-bottomed nanoflask—have been constructed by DNA origami

Rise of the Micromachines
Self-propelled microrockets that pickup and transport pancreatic tumor cells under physiological conditions have been developed

Angewandte Chemie 17/2011: A Good Catch
An overview of the latest edition of Angewandte Chemie

Total Synthesis of HIV-1 Rev Protein
Protein that plays an important role in the HIV replication cycle can now be synthesized chemically

Ice Cream, Organs, and Antifreeze Proteins
Understanding how antifreeze proteins from Antarctic bacterium bind to ice crystals could improve organ transplants and ice cream

Probing Intracellular Viscosity
Measuring intracellular viscosity could explain how molecules and signals are transported in diseases such as cystic fibrosis

Speeding Up Evolution
Fast-replicating bacterial viruses, phages, have been harnessed to accelerate the evolution of biomolecules in the laboratory