Poly(lactic-co-glycolic acid) nanoparticles wrapped with red blood cell membranes neutralize pore-forming toxins
Fooling Toxins with Mimetic Nanosponges
A Drug Discovery Detective Story
Biological activity of small-molecule RNA polymerase (RNAP) inhibitors revealed to come from polymeric impurity
Most Accessed Articles: April 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for April 2013
Frances Arnold Awarded Emanuel Merck Lectureship 2013
Professor Frances Arnold, Caltech, USA, has been awarded the Emanuel Merck Lectureship and will deliver a special public lecture
Meat, Bacteria, and Atherosclerosis
By metabolizing L-carnitine, a nutrient abundant in red meat, intestinal bacteria promote atherosclerosis
Discovery of Unexpectedly Active Group
Introduction of a sulfoximine group into anticancer candidates shows that sometimes sticking to the unconventional pays off
Exploiting Structural Differences in Serotonin Receptors
Serotonin receptors present structural differences which can be used to design agonistic drugs devoid of side effects
Health Warnings for Shampoos?
Personal care products carry no hazardous symbols as they are explicitly excluded from the regulation for labeling of chemicals
Hope for Hepatitis Drug
A straightforward synthesis of an antiviral drug, entecavir, to treat hepatitis B has industrial scale-up potential
New Route to Anticancer Agent Quinocarcin
Synthesis of quinocarcin through a convergent strategy based on Sonogashira coupling and gold(I)-catalyzed hydroamination