Nanomaterial made from lipids and silicon dioxide improves absorption of pharmaceuticals by imitating the food effect

Simulated Digestion for Better Drug Delivery

Graphene Capsules
A novel drug-delivery system can be built using capsules of composite graphene oxide and poly(allylamine hydrochloride)

New Biprivileged Molecular Scaffolds
Compounds with several heteroaromatic functionalities present multiple rigid privileged structures for drug discovery

Effective siRNA Delivery
siRNA polymerized for the first time in hydrogel particles for controlled intracellular delivery

Most Accessed Articles: March 2012
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for March 2012

Enhanced Contrast Media for Magnetic Resonance Imaging (MRI)
Micelles with enhanced chemical exchange saturation transfer (CEST) sensitivity synthesized

Enhanced Solubility and Bioactivity of Pharmaceuticals
Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals

Amgen Acquires KAI Pharmaceuticals
Acquisition holds opportunity to potentially deliver novel therapy for chronic kidney disease patients on dialysis suffering from secondary hyperparathyroidism

Marine Natural Product Stops Cancer Drug Resistance
Lamellarins, natural products isolated from marine mollusks and sponges, show potential in treating multidrug resistant cancer

Angewandte Chemie 16/2012: Activate!
An overview of the latest issue of Angewandte Chemie