Mechanochemistry enables a rapid, solvent-free synthesis of 5-amino-4-cyanoxazoles in just 10 minutes, achieving high yields with minimal waste


Mechanochemistry enables a rapid, solvent-free synthesis of 5-amino-4-cyanoxazoles in just 10 minutes, achieving high yields with minimal waste

Nickel-catalyzed coupling of alcohols with ketones also allows for a one-pot aminomethylation

Green, efficient, and regioselective synthesis of pyrazoles

Chiral phosphoric acid catalyst promotes formation of useful precursors for the synthesis of axially chiral compounds

Five new heterocyclic ring systems that could have uses in medicinal chemistry

Highlighting Larry E. Overman's outstanding contributions and celebrating his autobiography's launch with talks by former group members Martin Oestreich and Nobel Prize winner David MacMillan

Gochnatiolide D and ainsliadimer A prepared via a one-pot sequence using hexafluoroisopropanol (HFIP) as the solvent

Strategy using 1,1’-carbonyldiimidazole (CDI) as an activating agent allows for a straightforward synthesis of two bioactive iminosydnones

Highlighting the outstanding contributions of Larry E. Overman and to celebrate the launch of his autobiography

Efficient, environmentally friendly, copper-free approach uses an industrial surfactant