Mechanochemistry enables a rapid, solvent-free synthesis of 5-amino-4-cyanoxazoles in just 10 minutes, achieving high yields with minimal waste

Mechanochemistry enables a rapid, solvent-free synthesis of 5-amino-4-cyanoxazoles in just 10 minutes, achieving high yields with minimal waste
Nickel-catalyzed coupling of alcohols with ketones also allows for a one-pot aminomethylation
Green, efficient, and regioselective synthesis of pyrazoles
Chiral phosphoric acid catalyst promotes formation of useful precursors for the synthesis of axially chiral compounds
Five new heterocyclic ring systems that could have uses in medicinal chemistry
Highlighting Larry E. Overman's outstanding contributions and celebrating his autobiography's launch with talks by former group members Martin Oestreich and Nobel Prize winner David MacMillan
Gochnatiolide D and ainsliadimer A prepared via a one-pot sequence using hexafluoroisopropanol (HFIP) as the solvent
Strategy using 1,1’-carbonyldiimidazole (CDI) as an activating agent allows for a straightforward synthesis of two bioactive iminosydnones
Highlighting the outstanding contributions of Larry E. Overman and to celebrate the launch of his autobiography
Efficient, environmentally friendly, copper-free approach uses an industrial surfactant