Overview of the latest issue of Angewandte Chemie

Angewandte Chemie 25/2021: Dynamic Networks

SARS-CoV-2 Protease Can Target Human Proteins
Cleavage of host proteins by viral proteases could be related to COVID-19 symptoms

Enzymatic Friedel-Crafts Alkylations
Squalene-hopene cyclases provide a biological alternative to the traditional reaction

Nickel-Catalyzed Asymmetric Synthesis of Unnatural Amino Acids
Enantioconvergent coupling of racemic alkyl electrophiles with alkylzinc reagents, promoted by earth-abundant metal

Three-Component Staudinger Reaction
Synthesis of β-lactams from amines, aldehydes, and diazoketones

Hydrogels Can Firm Up Under Stress
Polyethylene glycol hydrogels crosslinked using sliding rings

Small and Versatile Highly Energetic Molecules
Small carbonyl azides synthesized and characterized

Lonza and Moderna Collaborate for Drug Substance Manufacturing
New mRNA production line in the Netherlands will support the manufacture of up to 300 million additional COVID-19 vaccine doses per year

Solar-Powered Whole-Cell P450 Catalysis
Photobiocatalysis as a green platform for driving redox enzymatic reactions using solar energy

Efficient Transamidation of Tertiary Alkyl Amides
Reaction uses tungsten(VI) chloride as a catalyst and chlorotrimethylsilane as an additive