Professor Virgil Percec discussed the discovery of Janus dendrimers, amphiphilic branched nanostructures that are able to self-assemble in water to form a variety of nanosized packets of different shapes capable of mimicking biological membranes, in the inaugral Kavali Foundation Innovations in Chemistry lecture at the 241st National Meeting of the American Chemical Society.
The potential applications of these so called dendrimersomes include the delivery of therapeutically relevant molecules to sites of interest in the body. Similar to liposomes, therapeutic agents can be encapsulated in these packets and delivered to the tumor site, circumventing toxicity or solubility issues. The advantage of dendrimersomes over liposomes, an established formulation method, is their stability and uniformity in size and dispersion.
While their full scope of application has yet to be established, the possibilities appear endless.
- Watch the video of the talk
Mimicking Mother Nature yields promising materials for drug delivery and other applications
Other articles related to the ACS meeting
- Removal of Strontium From Nuclear Waste
Removal of strontium from nuclear waste streams by desmid green algae
- Hollywood Chemistry
And the Winner for the Most Accurate Science in a Movie or TV series goes to …
- Kevlar-like Plastic from Pineapples and Bananas
Nano-cellulose fibers from plants may lead to stronger, lighter, and more sustainable materials to replace automotive plastics
- Charles Lathrop Parson Award
Michael E. Strem, president of high purity chemicals maker Strem Chemicals, receives the ACS award for outstanding public service
- Priestley Medal Awarded
Ahmed H. Zewail, California Institute of Technology, USA, awarded ACS’s highest honor Priestley Medal Awarded
- A New Class of Therapeutics
Staple peptides are able to address targets previously considered undruggable by conventional therapeutics