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Iterative Theory/Experiment Cycles
Integrated computational and experimental organic chemistry tools to investigate new multicomponent reactions

Revised Formation Mechanism
Mn/Re vinylidenes react with P–OR nucleophiles via hydrolysis rather than intramolecular Michaelis–Arbuzov rearrangement

Synthesis of gem-Difluoroalkenes
Trifluoromethyl-substituted alkenes react with radical precursors to produce 1,1-difluoroalkene carbonyl mimics

Boost the Nucleophilicity of Allylboron
Aryllithium enhances the nucleophilicity of allylboronate to react with a wide range of electrophiles

Hydrogel Microspheres Cross-Linked by Rotaxane Networks
Rotaxane cross-linked microgels show a decoupled thermo- and pH-responsive volume transition

Computationally Guided Catalyst Design
First catalyst-controlled asymmetric allenic Pauson-Khand reaciton guided by computational studies

Angewandte Chemie 45/2017: Changing of the Guard
Overview of the latest issue of Angewandte Chemie

Ronald C. D. Breslow (1931 – 2017)
Professor of Columbia University, New York, NY, USA, passed away

Chiral Propeller-Shaped Nanographenes
First large and chiral polyaromatic hydrocarbons with stable stereochemistry synthesized