Late-stage divergent synthetic route allows the synthesis of analogues of bleomycin, a common anticancer drug

Building Anticancer Drugs Without Side Effects

Chemical Poems: Fluorine
Poems based on the natural properties of each of the elements of the periodic table

Direct Imine Acylation
A direct method of coupling imines with carboxylic acids creates a wide range of heterocycles

Metal- and Oxidant-Free Direct sp3 C–H Arylation of Pyrrolidine
A simplified arylation of pyrrolidine offers an alternative to metal-mediated reactions

The Early Career Series
ChemPlusChem features up and coming researchers whose focus is on multidisciplinary research centering on chemistry

Angewandte Chemie 5/2013: Separate and Unite
Overview of the latest issue of Angewandte Chemie

Tetrahalogenated Spiroketals
Iodocyclization gives spirocyclic skeletons with four halogen substituents

Angewandte Chemie 4/2014: High Stability
Overview of the latest issue of Angewandte Chemie

Not Kicking Up a Stink
A three-component reaction is an alternative to thiols for making vinyl sulfides

Water-Soluble Boron Dyes
Application of red-emitting and water-soluble boron dyes for biosensing