A concise synthesis of a novel alkaloid natural product with the pyrroloindoloquinazoline skeleton has been devised

Concise Total Synthesis of a Newly Discovered Alkaloid

Angewandte Chemie 30/2013: A Shining Example
An overview of the latest issue of Angewandte Chemie

Squaring Up To Michael Additions
Organocatalytic continuous-flow Michael additions give great selectivity and good product diversity

Sugar Coating Reveals Black Death
Plague detection through anti-carbohydrate antibodies could lead to rapid point-of-care diagnosis

New Supramolecular Assembly with Exceptionally High Boron Content
A supramolecular cubooctahedron packed with 240 boron atoms has been synthesized using coordination-driven assembly

Conveying the Excitement of Chemistry on YouTube
Martyn Poliakoff, UK, and freelance filmmaker Brady Haran discuss how YouTube can be used to inspire the next generation of chemists

Enantioselective Carbene-Catalyzed Annulations
2-benzoxopinones were synthesized by a dual activation strategy, involving N-heterocyclic carbene catalysis and a second Lewis base

Extracting the Medicine from Traditional Chinese Medicine
Isolated compounds from Chinese medicine often show physiological activity. One such compound from Gansong has been identified

Malleobactin Structure Elucidated
The virulence factor malleobactin has been shown to contain an unprecedented nitro-bearing amino acid

A Spontaneous Resolution
Chiral supramolecular fluorophores can be made by simple crystallisation