Compounds with several heteroaromatic functionalities present multiple rigid privileged structures for drug discovery
New Biprivileged Molecular Scaffolds
Effective siRNA Delivery
siRNA polymerized for the first time in hydrogel particles for controlled intracellular delivery
Most Accessed Articles: March 2012
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for March 2012
Enhanced Contrast Media for Magnetic Resonance Imaging (MRI)
Micelles with enhanced chemical exchange saturation transfer (CEST) sensitivity synthesized
Enhanced Solubility and Bioactivity of Pharmaceuticals
Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals
Amgen Acquires KAI Pharmaceuticals
Acquisition holds opportunity to potentially deliver novel therapy for chronic kidney disease patients on dialysis suffering from secondary hyperparathyroidism
Marine Natural Product Stops Cancer Drug Resistance
Lamellarins, natural products isolated from marine mollusks and sponges, show potential in treating multidrug resistant cancer
Angewandte Chemie 16/2012: Activate!
An overview of the latest issue of Angewandte Chemie
Specificity by Ring Size
Bicyclic peptides with optimized ring size inhibit enzyme that cleaves peptide bonds while sparing paralogous proteases
Chemical Synthetic Biology
Book covering a dynamic new area of research at the interface of science and engineering is reviewed by S. Brakmann, TU Dortmund