Synthesis and biological characterization of amidopropenyl hydroxamates as histone deacetylase inhibitors for cancer treatment

An asymmetric total synthesis of the natural product erythro-8-O-4'-neolignan, machilin C, and its analog has been developed.

Building multifunctional chiral building blocks from materials like D-glutamic acid opens up synthetic routes to natural products.

Cells behave differently when in 2 D environments, such as Petri dishes, to more natural, 3 D structures such as those in the human body.

Wiley-VCH author and Angew. Chem. Advisory Board member, Carolyn Bertozzi will receive this year's $500,000 Lemelson-MIT Prize.

Histine modifications allow the Kaposi Sarcoma-associated herpesvirus (KSHV) to switch between latent and active states.

Evonik supplies China with catalysts from new Shanghai production facility

Overview on the current issue of the Angewandte Chemie International Edition.

Insights into the relationship between a self-rated health, morbidity and mortality, the underlying immunological mechanisms.

A new route for the synthesis of protoporphyrin IX avoids contamination with animal products and associated risks to human patients.