Potent class of RNA-virus-inhibiting (cyclo)depsipeptides

First Total Synthesis of Thiamyxins A–C and E

New Vaccine Concept against SARS-CoV-2 Successful in Animals
Vaccine based on a modified "single-cycle" virus that is incapable of replication

Three-Year Collaboration in Computational Catalysis Science
Merck Collaborates with John F. Hartwig's research groups based in Berkeley, CA, USA, on digital design of catalysts

Cobalt(II)-Mediated Three-Component Synthesis of 1,3,4-Oxadiazoles
Nitrene transfer followed by addition of a carboxylic acid and an intramolecular aza-Wittig reaction

Paul Bunge Prize 2023 for Robert W. Smith
Award honors studies on the history of scientific instruments

Template-Controlled Synthesis of Chiral MOFs
Chiral metal-organic frameworks (MOFs) grown via directed assembly on twisted bundles of cellulose nanocrystals

Path to β-Trifluoromethyl Imides
Visible-light-induced four-component reaction using CF3Br, alkenes, carboxylic acids, and nitriles

Light-Promoted Regioselective Germylation
Synthesis of germanium-containing spiro[4.5]trienones and vinylgermanes

A “Sterically Stressed” Amide as a Protecting Group for Amines
5-Chloro-8-nitro-1-naphthoyl (NNap) can be introduced as an acid chloride and removed under mild conditions

Multi-Enzyme Biosynthesis for the Production of 3-Amino-2-Hydroxy Acetophenone
Critical intermediate in the synthesis of asthma medication