New Route to Chiral Amides

New Route to Chiral Amides

One-pot method generates chiral amides from secondary alcohols with retention of stereochemistry and provides evidence for non-planar carbocations

New Method for Adding Alkyl Groups

New Method for Adding Alkyl Groups

New method for adding methyl groups to aldehydes gives the highest enantioselectivities and yields reported and can be used for longer alkyl chains

A Reality Check for Cancer

A Reality Check for Cancer

Software screens virtual multi-component reaction products which can be rapidly synthesized and undergo a reality check by physical screening