Cross-coupling of alkyl acids, alkynes, and [1.1.1]propellane
![Three-Component Reaction Gives Substituted Bicyclo[1.1.1]pentanes](https://www.chemistryviews.org/wp-content/uploads/2022/06/propellane-125x94.jpg)
Three-Component Reaction Gives Substituted Bicyclo[1.1.1]pentanes

Regioselective Carboboration of Terminal Alkynes
Cyclic(alkyl)(amino)carbene (CAAC) ligands favor α-selectivity in copper-catalyzed reaction

Nonactivated Cyclopropanes Used to Prepare Lactams
Secondary amines and anilines as directing groups for carbonylative C–C bond insertions

Dimeric Ni(I) Methyl Complex
Dimeric complex with bridging methyl groups shows interesting reactivity

Synthesis of Thienopyrrolediones from Simple Starting Materials
Transition-metal-free reaction using elemental sulfur, aldehydes, and β-ketoamides

Hydroaminocarbonylation of Unsymmetrical Internal Alkynes
Path to α,β-unsaturated amides

Azabuckybowl-Helicene Hybrid Synthesized
First example of a chiral nanographene containing five [7]helicenes in a fused π-system

Can SARS-CoV-2 Spike Protein Fragments Misfold?
Amyloid structures could be important for understanding COVID-19 and long COVID

New Rearrangement Gives Highly Substituted Aziridines
Aza-quasi-Favorskii reaction realized

Concise Path to 2-Arylindole-Based Fungicide Candidates
Efficient one-pot synthesis of a variety of 2-arylindole derivatives