Integrated process for the preparation of a widely used anti-inflammatory drug

Continuous Flow Synthesis of Diclofenac Sodium

Concise Path to 2-Arylindole-Based Fungicide Candidates
Efficient one-pot synthesis of a variety of 2-arylindole derivatives

Concise Synthesis of Anticancer Drug Candidates
Enzyme inhibitor tunicamycin V prepared via a Büchner-Curtius-Schlotterbeck-type reaction

Hybrid Prodrug Can Release NO and H2S to Fight Heart Failure
Enzyme-responsive compound as a source of signaling molecules

A New Target to Combat Bacterial Infections
Enzymes from the branched-chain amino acid biosynthesis pathway as targets for drug development

Genetic Signature of a Toxin Allows Cyanobacterial Bloom Monitoring
Insights into the biosynthesis of guanitoxin enable environmental detection

Synthesis of δ-Halogenated Sulfonyl Amides
Halogenation reactions enabled by a nitrogen-centered radical precursor

Biocatalyzed Aldol Addition for Industrial Applications
Useful reaction for the synthesis of drug precursors

Antimicrobial Air Filters for Cars
Polyester filter media coated with CuO nanoparticles

Most Accessed Articles: April 2022
Highlights from Chemistry Europe, ACES, and GDCh journals