Rhodium(III)-catalyzed C–H activation and annulation in ethanol

Green Synthesis of 3,4-Unsubstituted Isoquinolones

Dual Target Inhibitor Blocks Cancer Cell Migration
Compound induces apoptosis and hinders cell migration

Combining Biocatalysis with a Biocompatible Reaction for One-Pot Syntheses
Biocatalyzed alcohol oxidation and chemocatalyzed Pictet-Spengler annulation give tetrahydroisoquinolines and tryptolines

Gold-Catalyzed Regiodivergent Synthesis of Carbazoles
Catalyst- and substrate-controlled transformation via cyclization of indole-functionalized alkynols

Most Accessed Articles: September 2023
Highlights from Chemistry Europe, ACES, and GDCh journals

Stabilizing the Antibacterial Natural Product Pseudouridimycin
Modified analogues as promising starting points for drug development

Stereoselective Biocatalytic α-Deuteration of L-Amino Acids
Pyridoxal 5'-phosphate-dependent Mannich cyclase can deuterate a diverse range of amino acids

Path to Optically Active Sulfoxides
Method based on enzymatic resolution of α-sulfinyl esters followed by decarboxylative functionalization

Benzoxazole–Estradiol Chimeras with Anticancer Activity
Benzoxazoles have diverse pharmacological activities; estradiol derivatives can serve as anticancer agents

Catalyst-Free Photochemical Aerobic Oxidation of Boronic Acids
Reaction under UV-A light gives phenols and aliphatic alcohols