Overview of the latest issue of Angewandte Chemie

Angewandte Chemie 44/2022: A Need for Chemists

Trifluoromethylative Thiolation of Alkenes
Path to 1,2-bis(trifluoromethylated) compounds

First Total Synthesis of Havellockate
Complex polycyclic structure with a highly oxygenated tricyclic core and a spiro-fused ring

Subporphyrin Free Bases Synthesized
Ring-contracted porphyrins consisting of three pyrroles and three meso-carbons

Commercial Process for the Synthesis of Anti-Cancer Drug Sotorasib
Transformation of the established early synthesis route for sotorasib into an efficient large-scale process

Peri‐Functionalized Tetraazaperylenes
Polycyclic aromatic compounds show promise as strong emitters

Metal-Free C–H Borylation of Electron-Rich Alkenes
Path to borylated compounds which can be further functionalized in a one-pot approach

Catalyst‐Free C–F Activation of 3-Perfluoroalkyl Indoles
Reaction allows the introduction of a nucleophile in the perfluorinated side chain

Angewandte Chemie 43/2022: Highly Advantageous
Overview of the latest issue of Angewandte Chemie

Crown Ether Reads Out Stereochemistry along a Molecular Tape
Information obtained from circular dichroism response of a small-molecule "reading head"