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FEBS Journal

Spatial and temporal key steps in early‐life intestinal immune system development and education

Published: 20 June 2021

Author(s): Camille Wagner, Natalia Torow, Mathias W. Hornef, Hugues Lelouard

Education of our intestinal immune system early in life strongly influences adult health. This education strongly relies on series of events that must occur in well‐defined time windows. From initial colonization by maternal‐derived microbiota during delivery to dietary changes from mother's milk to solid foods at weaning, these early‐life events have indeed long‐standing consequences on our immunity, facilitating tolerance to environmental exposures or, on the contrary, increasing the risk of...

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Chemical Biology & Drug Design

Dithiocarbamate derivatives inhibit α‐glucosidase through an apparent allosteric site on the enzyme

Published: 20 June 2021

Author(s): Usman Ghani, Sajda Ashraf, Zaheer Ul‐Haq, Ahmed H. Mujamammi, Yusuf Özkay, Fatih Demirci, Zafer Asim Kaplancikli

Abstract Dithiocarbamate derivatives possess diverse biological activities. This work further expands their activity profile by identifying seven benzylamine‐containing dithiocarbamate derivatives with piperazine and piperidine substitutions at the main moiety, and five piperazine‐containing dithiocarbamates with various substitutions at the piperazine moiety as new inhibitors of α‐glucosidase. Compounds bearing the benzylamine moiety exhibited more potent inhibition of the enzyme than the...

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Comprehensive Reviews in Food Science and Food Safety

Bacillus spore germination at moderate high pressure: A review on underlying mechanisms, influencing factors, and its comparison with nutrient germination

Published: 19 June 2021

Author(s): Alessia I. Delbrück, Yifan Zhang, Rosa Heydenreich, Alexander Mathys

Abstract Spore‐forming bacteria are resistant to stress conditions owing to their ability to form highly resistant dormant spores. These spores can survive adverse environmental conditions in nature, as well as decontamination processes in the food and related industries. Bacterial spores may return to their vegetative state through a process called germination. As spore germination is critical for the loss of resistance, outgrowth, and development of pathogenicity and spoilage potential, the...

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Comprehensive Reviews in Food Science and Food Safety

Food‐grade carrageenans and their implications in health and disease

Published: 19 June 2021

Author(s): Fang Liu, Pengfen Hou, Hui Zhang, Qingjuan Tang, Changhu Xue, Robert W. Li

Abstract Food additives, often used to guarantee the texture, shelf‐life, taste, and appearance of processed foods, have gained widespread attention due to their increased link to the growing incidence of chronic diseases. As one of the most common additives, carrageenans have been used in human diets for hundreds of years. While classified as generally recognized as safe (GRAS) for human consumption, numerous studies since the 1980s have suggested that carrageenans, particularly those with...

thumbnail image: Comprehensive Reviews in Food Science and Food Safety

Comprehensive Reviews in Food Science and Food Safety

Challenges associated with spray drying of lactic acid bacteria: Understanding cell viability loss

Published: 19 June 2021

Author(s): Maria Tereza Cratiú Moreira, Evandro Martins, Ítalo Tuler Perrone, Rosângela Freitas, Lucas Sales Queiroz, Antônio Fernandes Carvalho

Abstract Lactic acid bacteria (LAB) cultures used in food fermentation are often dried to reduce transportation costs and facilitate handling during use. Dried LAB ferments are generally lyophilized to ensure high cell viability. Spray drying has come to the forefront as a promising technique due to its versatility and lower associated energy costs. Adverse conditions during spray drying, such as mechanical stress, dehydration, heating, and oxygen exposure, can lead to low LAB cell viability....

thumbnail image: Comprehensive Reviews in Food Science and Food Safety

Comprehensive Reviews in Food Science and Food Safety

Recent developments of natural antimicrobials and antioxidants on fish and fishery food products

Published: 19 June 2021

Author(s): Nikheel Bhojraj Rathod, Rahul Chudaman Ranveer, Soottawat Benjakul, Se‐Kwon Kim, Asif Umar Pagarkar, Surendra Patange, Fatih Ozogul

Abstract Fish and fishery products (FFP) are highly perishable due to their high nutritional value and moisture content. The spoilage is mainly caused by microorganisms and chemical reactions, especially lipid oxidation, leading to losses in quality and market value. Microbiological and lipid deteriorations of fishery‐derived products directly lower their nutritive value and pose the risk of toxicity for human health. Increasing demand for safe FFP brings about the preservation using additives...

thumbnail image: Comprehensive Reviews in Food Science and Food Safety

Comprehensive Reviews in Food Science and Food Safety

Wine phenolic profile altered by yeast: Mechanisms and influences

Published: 19 June 2021

Author(s): Pangzhen Zhang, Wen Ma, Yiqi Meng, Yifan Zhang, Gang Jin, Zhongxiang Fang

Abstract Grape phenolic compounds undergo various types of transformations during winemaking under the influences of yeasts, which further impacts the sensory attributes, thus the quality of wine. Understanding the roles of yeasts in phenolics transformation is important for controlling wine quality through fermentation culture selection. This literature review discusses the mechanisms of how yeasts alter the phenolic compounds during winemaking, summarizes the effects of Saccharomyces...

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Comprehensive Reviews in Food Science and Food Safety

Food polysaccharides and roles of rheology and tribology in rational design of thickened liquids for oropharyngeal dysphagia: A review

Published: 19 June 2021

Author(s): Pawadee Methacanon, Chaiwut Gamonpilas, Akapong Kongjaroen, Chonchanok Buathongjan

Abstract In today's market environment, an aging society is recognized as one of the megatrends in the world. The demographic change in the world population age structure has driven a huge demand in healthcare products as well as services that include the technological innovation for the health and wellness of the elderly. Dysphagia or swallowing difficulty is a common problem in the elderly as many changes in swallowing function come with aging. The presence of a strong relationship between...

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Comprehensive Reviews in Food Science and Food Safety

Avocado oil: Production and market demand, bioactive components, implications in health, and tendencies and potential uses

Published: 19 June 2021

Author(s): Braulio Cervantes‐Paz, Elhadi M. Yahia

Abstract Avocado is a subtropical/tropical fruit with creamy texture, peculiar flavor, and high nutritional value. Due to its high oil content, a significant quantity of avocado fruit is used for the production of oil using different methods. Avocado oil is rich in lipid‐soluble bioactive compounds, but their content depends on different factors. Several phytochemicals in the oil have been linked to prevention of cancer, age‐related macular degeneration, and cardiovascular diseases and...

thumbnail image: Comprehensive Reviews in Food Science and Food Safety

Comprehensive Reviews in Food Science and Food Safety

Sensory evaluation of fresh/frozen mackerel products: A review

Published: 19 June 2021

Author(s): Yi‐Zhen Huang, Yu Liu, Zheng Jin, Qiaofen Cheng, Michael Qian, Bei‐Wei Zhu, Xiu‐Ping Dong

Abstract Mackerel has received considerable attention in the global food market as one of the most important pelagic commercial fish species. The quality of mackerel is influenced by species, season, fishing area, nutritional status, catching method, handling, and storage. Due to the mackerel's perishability, its quality is mainly measured by sensory procedures. Although considerable effort has been made to explore quick and reliable quality analysis, developing a practical and scientific...

thumbnail image: Comprehensive Reviews in Food Science and Food Safety

Most-accessed articles from each Chemistry Europe, ACES, and GDCh journal

May 2021


Fang Zhang, Juewen Liu
Label-Free Colorimetric Biosensors Based on Aptamers and Gold Nanoparticles: A Critical Review [Review]
Anal. Sens. 2021, vol. 1, no. 1, p. 30

Rola Houhou, Thomas Bocklitz
Trends in artificial intelligence, machine learning, and chemometrics applied to chemical data [Review]
Anal. Sci. Adv. 2021, vol. 2, no. 3-4, p. 128

Hassna El-Bousiydy, Teo Lombardo, Emiliano N. Primo, Marc Duquesnoy, Mathieu Morcrette, Patrik Johansson, Patrice Simon, Alexis Grimaud, Alejandro A. Franco
What Can Text Mining Tell Us About Lithium-Ion Battery Researchers’ Habits? [Concept]
Batteries Supercaps 2021, vol. 4, no. 5, p. 758

Hemanth Maddali, Catherine E. Miles, Joachim Kohn, Deirdre M. O'Carroll
Optical Biosensors for Virus Detection: Prospects for SARS-CoV-2/COVID-19 [Minireview]
ChemBioChem 2021, vol. 22, no. 7, p. 1176

Christian M. Heckmann, Francesca Paradisi
Looking Back: A Short History of the Discovery of Enzymes and How They Became Powerful Chemical Tools [Review]
ChemCatChem 2020, vol. 12, no. 24, p. 6082

Pooja Vadhva, Ji Hu, Michael J. Johnson, Richard Stocker, Michele Braglia, Dan J. L. Brett, Alexander J. E. Rettie
Electrochemical Impedance Spectroscopy for All-Solid-State Batteries: Theory, Methods and Future Outlook [Review]
ChemElectroChem 2021, vol. 8, no. 11, p. 1930

Michał Rams, Aleksej Jochim, Michael Böhme, Thomas Lohmiller, Magdalena Ceglarska, Marek M. Rams, Alexander Schnegg, Winfried Plass, Christian Näther
Single-Chain Magnet Based on Cobalt(II) Thiocyanate as XXZ Spin Chain [Full Paper]
Chem. Eur. J. 2020, vol. 26, no. 13, p. 2837

Iris C. ten Have, Adriaan J. A. Duijndam, Ramon Oord, Hannie J. M. Berlo-van den Broek, Ina Vollmer, Bert M. Weckhuysen, Florian Meirer
Photoinduced Force Microscopy as an Efficient Method Towards the Detection of Nanoplastics [Communication]
Chem. Methods 2021, vol. 1, no. 5, p. 205

Zheng-Wang Qu, Hui Zhu, Sergey A. Katsyuba, Vera L. Mamedova, Vakhid A. Mamedov, Stefan Grimme
Acid-Catalyzed Rearrangements of 3-Aryloxirane-2-Carboxamides: Novel DFT Mechanistic Insights [Communication]
ChemistryOpen 2020, vol. 9, no. 7, p. 743

Miaofang Chi, Harry M. Meyer, Zili Wu, Liangbo Liang, Peter V. Bonnesen, Dale K. Hensley, Rui Peng, Yang Song, Cheng Ma, Bobby G. Sumpter, Adam J. Rondinone
High-Selectivity Electrochemical Conversion of CO2 to Ethanol using a Copper Nanoparticle/N-Doped Graphene Electrode [Full Paper]
ChemistrySelect 2016, vol. 1, no. 19, p. 6055

Antoine Daina, Vincent Zoete
A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules [Communication]
ChemMedChem 2016, vol. 11, no. 11, p. 1117

Sebastian Gisbertz, Bartholomäus Pieber
Heterogeneous Photocatalysis in Organic Synthesis [Review]
ChemPhotoChem 2020, vol. 4, no. 7, p. 456

Trevor A. Hamlin, Marcel Swart, F. Matthias Bickelhaupt
Nucleophilic Substitution (SN2): Dependence on Nucleophile, Leaving Group, Central Atom, Substituents, and Solvent [Minireview]
ChemPhysChem 2018, vol. 19, no. 11, p. 1315

Daewoo Han, Andrew J. Steckl
Coaxial Electrospinning Formation of Complex Polymer Fibers and their Applications [Review]
ChemPlusChem 2019, vol. 84, no. 10, p. 1453

Layla Filiciotto, Gadi Rothenberg
Biodegradable Plastics: Standards, Policies, and Impacts [Review]
ChemSusChem 2021, vol. 14, no. 1, p. 56

Anton I. Hanopolskyi, Viktoryia A. Smaliak, Alexander I. Novichkov, Sergey N. Semenov
Autocatalysis: Kinetics, Mechanisms and Design [Review]
ChemSystemsChem 2021, vol. 3, eLoc. e2000026

Rasha Rahman Poolakkandy, Mini Mol Menamparambath
Transition metal oxide based non-enzymatic electrochemical sensors: An arising approach for the meticulous detection of neurotransmitter biomarkers [REVIEW]
Electrochem. Sci. Adv. 2021, vol. 1, eLoc. e2000024

Alana M. Homrich, Giliandro Farias, Suélen M. Amorim, Fernando R. Xavier, Rogério A. Gariani, Ademir Neves, Hernán Terenzi, Rosely A. Peralta
Effect of Chelate Ring Size of Binuclear Copper(II) Complexes on Catecholase Activity and DNA Cleavage [Full Paper]
Eur. J. Inorg. Chem. 2021, p. 1710

Luca Capaldo, Davide Ravelli
Hydrogen Atom Transfer (HAT): A Versatile Strategy for Substrate Activation in Photocatalyzed Organic Synthesis [Microreview]
Eur. J. Org. Chem. 2017, p. 2056

Catharina Goedecke
Why Does Iodine Turn Starch Blue?
ChemViews Magazine 2016

Shoji Kobayashi, Keisuke Shibukawa, Yuta Miyaguchi, Araki Masuyama
Grignard Reactions in Cyclopentyl Methyl Ether [Full Paper]
Asian J. Org. Chem. 2016, vol. 5, no. 5, p. 636

Sandip G. Agalave, Suleman R. Maujan, Vandana S. Pore
Click Chemistry: 1,2,3‐Triazoles as Pharmacophores [Focus Review]
Chem. Asian J. 2011, vol. 6, no. 10, p. 2696

Hongguang Song, Dong Liu, Jia Yang, Lei Wang, Hangxun Xu, Yujie Xiong
Highly Crystalline Mesoporous Silicon Spheres for Efficient Visible Photocatalytic Hydrogen Evolution [Communication]
ChemNanoMat 2017, vol. 3, no. 1, p. 22

Xinlan A. F. Cook, Antoine Gombert, Janette McKnight, Loïc R. E. Pantaine, Michael C. Willis
The 2-Pyridyl Problem: Challenging Nucleophiles in Cross-Coupling Arylations [Review]
Angew. Chem. Int. Ed. 2021, vol. 60, no. 20, p. 11068

Abas Mohsenzadeh, Akram Zamani, Mohammad J. Taherzadeh
Bioethylene Production from Ethanol: A Review and Techno-economical Evaluation [Review]
ChemBioEng Rev. 2017, vol. 4, no. 2, p. 75

Özge Çepelioğullar Mutlu, Thomas Zeng
Challenges and Opportunities of Modeling Biomass Gasification in Aspen Plus: A  Review [Review]
Chem. Eng. Technol. 2020, vol. 43, no. 9, p. 1674

Nuria Sánchez-Bastardo, Robert Schlögl, Holger Ruland
Methane Pyrolysis for CO2-Free H2 Production: A Green Process to Overcome Renewable Energies Unsteadiness [Review]
Chem. Ing. Tech. 2020, vol. 92, no. 10, p. 1596

Emiliano Feresin*, Mykhailo Kondratiuk, Julia Nowack, Lukas Gooßen*
Handreinigung auf molekularer Ebene - Die Rolle der Solvatation [Artikel]
Chem. Unserer Zeit 2021, vol. 55, no. 1, p. 28

Hilbert Meyer
Guter Unterricht an guten Schulen? [Aufsatz]
CHEMKON 2006, vol. 13, no. 2, p. 77

Editorial Lebensmittelchemie 1/2021 [Editorial]
Lebensmittelchemie 2021, vol. 75, no. 1, p. 1

Frauke Zbikowski
„Ein gewisser Jagdinstinkt“ [Bildung + Gesellschaft]
Nachr. Chem. 2021, vol. 69, no. 5, p. 8

Most cited articles from Chemistry Europe, ACES, and GDCh journals

Articles on this list are the most frequently cited ones among those published in 2017 or 2018 according to Web of Science. They have contributed the most to the journal's impact factor in 2019.


Yuanjun Chen, Shufang Ji, Yanggang Wang, Juncai Dong, Wenxing Chen, Zhi Li, Rongan Shen, Lirong Zheng, Zhongbin Zhuang, Dingsheng Wang, Yadong Li
Isolated Single Iron Atoms Anchored on N-Doped Porous Carbon as an Efficient Electrocatalyst for the Oxygen Reduction Reaction [Communication]
Angew. Chem. Int. Ed. 2017, vol. 56, pp. 6937–6941

Qian Sun, Kah Chun Lau, Dongsheng Geng, Xiangbo Meng
Atomic and Molecular Layer Deposition for Superior Lithium-Sulfur Batteries: Strategies, Performance, and Mechanisms [Review]
Batteries Supercaps 2018, vol. 1, pp. 41–68

Lik Hang Yuen, Raphael M. Franzini
Achievements, Challenges, and Opportunities in DNA-Encoded Library Research: An Academic Point of View [Minireview]
ChemBioChem 2017, vol. 18, pp. 829–836

Konstantinos C. Christoforidis, Paolo Fornasiero
Photocatalytic Hydrogen Production: A Rift into the Future Energy Supply [Review]
ChemCatChem 2017, vol. 9, pp. 1523–1544

Marwa Elkady, Hassan Shokry, Hesham Hamad
Microwave-Assisted Synthesis of Magnetic Hydroxyapatite for Removal of Heavy Metals from Groundwater [Research Article]
Chem. Eng. Technol. 2018, vol. 41, pp. 553–562

Massimo Baroncini, Lorenzo Casimiro, Christiaan de Vet, Jessica Groppi, Serena Silvi, Alberto Credi
Making and Operating Molecular Machines: A Multidisciplinary Challenge [Minireview]
ChemistryOpen 2018, vol. 7, pp. 169–179

Hanshen Xin, Xike Gao
Application of Azulene in Constructing Organic Optoelectronic Materials: New Tricks for an Old Dog [Minireview]
ChemPlusChem 2017, vol. 82, pp. 945–956

Hojat Veisi, Mozhgan Pirhayati, Ali Kakanejadifard, Pourya Mohammadi, Mohammad Reza Abdi, Javad Gholami, Saba Hemmati
In Situ Green Synthesis of Pd Nanoparticles on Tannic Acid-Modified Magnetite Nanoparticles as a Green Reductant and Stabilizer Agent: Its Application as a Recyclable Nanocatalyst (Fe3O4@TA/Pd) for Reduction of 4-Nitrophenol and Suzuki Reactions [Full Paper]
ChemistrySelect 2018, vol. 3, pp. 1820–1826

Jaqueline Daniel-Gromke, Nadja Rensberg, Velina Denysenko, Walter Stinner, Tina Schmalfuß, Mattes Scheftelowitz, Michael Nelles, Jan Liebetrau
Current Developments in Production and Utilization of Biogas and Biomethane in Germany [Review]
Chem. Ing. Tech. 2018, vol. 90, pp. 17–35

Sayantani Sikdar, Madhusree Kundu
A Review on Detection and Abatement of Heavy Metals [Review]
ChemBioEng Rev. 2018, vol. 5, pp. 18–29

Tingting Liu, Lisi Xie, Jianhui Yang, Rongmei Kong, Gu Du, Abdullah M. Asiri, Xuping Sun, Liang Chen
Self-Standing CoP Nanosheets Array: A Three-Dimensional Bifunctional Catalyst Electrode for Overall Water Splitting in both Neutral and Alkaline Media [Communication]
ChemElectroChem 2017, vol. 4, pp. 1840–1845

Ruibin Wang, Liheng Chen, J.Y. Zhu, Rendang Yang
Tailored and Integrated Production of Carboxylated Cellulose Nanocrystals (CNC) with Nanofibrils (CNF) through Maleic Acid Hydrolysis [Full Paper]
ChemNanoMat 2017, vol. 3, pp. 328–335

Chengwei Liu, Michal Szostak
Twisted Amides: From Obscurity to Broadly Useful Transition-Metal-Catalyzed Reactions by N−C Amide Bond Activation [Minireview]
Chem. Eur. J. 2017, vol. 23, pp. 7157–7173

Jian Shu, Dianping Tang
Current Advances in Quantum-Dots-Based Photoelectrochemical Immunoassays [Focus Review]
Chem. Asian J. 2017, vol. 12, pp. 2780–2789

Jian Rong, Chuanfa Ni, Jinbo Hu
Metal-Catalyzed Direct Difluoromethylation Reactions [Focus Review]
Asian J. Org. Chem. 2017, vol. 6, pp. 139–152

Juan Alberto Sirvent, Ulrich Lücking
Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates [Full Paper]
ChemMedChem 2017, vol. 12, pp. 487–501

Grzegorz Greczynski, Lars Hultman
C 1s Peak of Adventitious Carbon Aligns to the Vacuum Level: Dire Consequences for Material's Bonding Assignment by Photoelectron Spectroscopy [Communication]
ChemPhysChem 2017, vol. 18, pp. 1507–1512

Jia-Rong Chen, Dong-Mei Yan, Qiang Wei, Wen-Jing Xiao
Photocascade Catalysis: A New Strategy for Cascade Reactions [Concept]
ChemPhotoChem 2017, vol. 1, pp. 148–158

Zhiming Pan, Yun Zheng, Fangsong Guo, Pingping Niu, Xinchen Wang
Decorating CoP and Pt Nanoparticles on Graphitic Carbon Nitride Nanosheets to Promote Overall Water Splitting by Conjugated Polymers [Communication]
ChemSusChem 2017, vol. 10, pp. 87–90

Enzo Alessio
Thirty Years of the Drug Candidate NAMI-A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective [Microreview]
Eur. J. Inorg. Chem. 2017, pp. 1549–1560

Marcel Garbe, Kathrin Junge, Matthias Beller
Homogeneous Catalysis by Manganese-Based Pincer Complexes [Microreview]
Eur. J. Org. Chem. 2017, pp. 4344–4362

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Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH