Derivatives of natural products with anticancer activity synthesized via a concise route

Hybrid Analogue of Pancratistatin Made from Shikimic Acid

Carboiodanation of Arynes Using Organoiodine(III) Reagents
Unique nucleophilic reactivity allows for additions across the C−C triple bond of arynes

€4.2M Project Promotes Non-Animal Chemical Safety Assessments
European Chemicals Agency (ECHA) commissions consortium to research alternatives to animal testing

Sugars Stabilize Collagen Triple Helices
Common carbohydrates as co-solutes increase the melting temperature

Mesoionic Janus-Type Dicarbenes Form Bimetallic Complexes
Two carbene centers on a single ring can bind two metals with short intermetallic distances

C4-Selective Carboxylation of Pyridines Using CO2
Copper-catalyzed reaction via pyridylphosphonium salts

New Company Aims to Lead in Acrylic and Polycarbonate Sheets
Röhm and Sabic to merge businesses into new company Polyvantis

What is a Founding Angel?
Business Angels, who invest in companies in the start-up phase, are now an established business model. But what are Founding Angels?

A Cubic Cu58 Nanocluster Protected by Bowl-Shaped Ligands
Phosphangulene-protected clusters can interact with fullerenes

Nucleotide Derivatives with Increased Reactivity
Prolinyl nucleotides with higher reactivity created by introducing substituents at the pyrrolidine ring