SARS-CoV-2 Virus

  • Author: ChemistryViews.org
  • Published Date: 26 March 2020
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
thumbnail image: SARS-CoV-2 Virus

What We Know About the Coronavirus

The coronavirus SARS-CoV-2 causes the current outbreak of the respiratory disease COVID-19. The virus was first detected in Wuhan, China, in December 2019 and has spread globally by now. The Center for Systems Science and Engineering (CSSE) at Johns Hopkins University, Baltimore, MD, USA, provides current updates of coronavirus COVID-19 global cases. The World Health Organization (WHO), which declared the rapidly spreading coronavirus outbreak a pandemic, describes how to protect yourself.

Below, you will find articles that have appeared on ChemistryViews covering the following topics:

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Virus Transmission and Protective Measures

SARS-CoV-2 Viral Load Levels and Infectiousness in Different Patient Groups

27 May 2021

Large study of viral loads allows estimations of the effects of age group and disease severity

Copper Nanowire Foams for Reusable Air Filters

03 April 2021

Possible face mask material provides high particulate filtration performance and is easy to clean, reuse, and recycle

What Can Stores Do to Prevent COVID-19 Transmission?

03 March 2021

One-way aisles prevent transmission by close contact; other measures are needed to avoid exposure to aerosols

Aerosol Transmission in Cruise-Ship COVID-19 Outbreak

19 February 2021

Scenarios based on the Diamond Princess outbreak show the importance of airborne transmission

Simulation Shows How SARS-CoV-2 Moves through a Restaurant

12 February 2021

Detailed investigation of known outbreak shows roles of ventilation and air conditioning

How Innate Immunity Influences COVID-19 Viral Load

23 January 2021

Mathematical model of SARS-CoV-2 infection dynamics developed

What Makes Some Groups More Vulnerable to COVID-19?

11 December 2020

SARS-CoV-2 infectivity might depend on the host's redox status

Spread and Mutations of SARS-CoV-2 in Austria Analyzed

25 November 2020

National-scale analysis of COVID-19 superspreading during the first wave of infections in the spring

Cloth Face Masks that Disinfect Themselves in Sunlight

21 November 2020

Functionalized cotton fabrics produce reactive oxygen species (ROS) under light exposure

How COVID-19 Spreads in Meat Processing Plants

08 November 2020

Investigation of outbreak at German meat processing plant shows important factors for virus spread

Heated Face Mask Could Inactivate SARS-CoV-2

Heated Face Mask Could Inactivate SARS-CoV-2

01 November 2020

Researchers aim to build masks with a heated copper mesh

New Model for Droplet Physics Could Inform COVID-19 Guidelines

New Model for Droplet Physics Could Inform COVID-19 Guidelines

29 October 2020

Masks and distancing are helpful, but might not be enough to prevent all contact with the virus

How Far Can Speech-Induced Airflow Carry Viruses?

29 September 2020

Plosive sounds like "p" form air puffs that can transport aerosols over 2 m in 30 s

Simple Method to Test the Efficacy of Face Masks

12 August 2020

Fast, low-cost estimation of droplet retention by different types of masks

How Well Do Face Masks Stop Droplets?

4 July 2020

Simple visualization experiments show effects of mask fit, materials, and layers

Replaceable Filter Membrane for More Efficient Face Masks

26 May 2020

Nanoporous hydrophobic polymer membrane developed

Unrecognized Infection Could Play Mayor Role in Spread of COVID-19
18 March 2020
Model that includes undocumented cases explains rapid growth in the number of infections

How Long Can the SARS-CoV-2 Virus Live on Surfaces and in Aerosols?
14 March 2020
New results on the stability of the virus causing COVID-19

Clever Picture
Coronavirus Entering and Replicating in a Host Cell
3 March 2020
https://doi.org/10.1002/chemv.202000018
Where the coronavirus comes from and how it infects the human body

How Long Can Coronaviruses Live on Surfaces?
13 February 2020
Literature review finds coronaviruses could persist on hard surfaces for up to nine days, but can be killed with the right disinfectant





Vaccines and Immunity

 Overview of Coronavirus Variants

Clever Picture: Overview of Coronavirus Variants

06 July 2021

Most mutations of SARS-CoV-2 do not have a noticeable impact on us, but some do – we look at which ones and why

COVID-19 Antibody Responses after Vaccines and Infections

26 June 2021

Antibody levels indicate need for two vaccine doses in those not infected before, single dose for those with past COVID-19, and booster shots for everybody

Mixed Vaccinations Generate Strong Immune Response

23 June 2021

Combination of AstraZeneca vaccine as first dose and BioNTech/Pfizer vaccine as second dose could be beneficial, according to preprint

Novavax's COVID-19 Vaccine Candidate

Novavax's COVID-19 Vaccine Candidate

15 June 2021

Shows 90 % overall efficacy and 100 % protection against moderate and severe disease in Phase 3 study, according to manufacturer

Lonza and Moderna Collaborate for Drug Substance Manufacturing

08 June 2021

New mRNA production line in the Netherlands will support the manufacture of up to 300 million additional COVID-19 vaccine doses per year

Impurities in AstraZeneca Vaccine Could Be Linked to Adverse Effects

30 May 2021

Vaccine contains process-related protein impurities, according to preprint

Merck Accelerates Scale Up of Lipids for mRNA Covid-19 Vaccines

Merck Accelerates Scale Up of Lipids for mRNA Covid-19 Vaccines

26 May 2021

New, high-purity synthetic cholesterol product launched nine months ahead of schedule

Second-Generation COVID-19 Vaccine Candidate

18 May 2021

CureVac and GSK aim to jointly develop vaccine candidates that offer improved immune responses and target emerging variants

Discussion on Patent Release for COVID-19 Vaccines

07 May 2021

According to industry association, lifting patent protection could discourage entrepreneurs and will not speed up the global supply of vaccines

Clever Picture: Comparing COVID-19 Vaccines

04 May 2021

Four Covid-19 vaccines have been approved in the EU to date

Interview: Ingmar Hoerr, Pioneer of mRNA Technology

04 May 2021

As a Ph.D. student, Hoerr discovered that mRNA can be used as a therapeutic vaccine or agent when administered directly into tissues

Simple Indicator Ensures Ultracold Supply Chain for mRNA Vaccines

04 April 2021

Alerting health care workers to unsafe temperatures during transport

Single Shot of COVID-19 Vaccine Boosts Antibodies in Recovered Patients

27 March 2021

Vaccinating previously infected persons could improve protection against multiple virus variants

First Single-Shot COVID-19 Vaccine

First Single-Shot COVID-19 Vaccine

02 March 2021

Johnson & Johnson's vaccine receives emergency approval from U.S. FDA

Lipid Production for mRNA-Based Vaccines in Germany

16 February 2021

Evonik is investing in the production of lipids at its Hanau and Dossenheim sites

New BioNTech Plant in Marburg, Germany

10 February 2021

This new BioNTech site will become one of the largest mRNA manufacturing sites in Europe

Next-Generation mRNA Vaccine Against COVID-19

Next-Generation mRNA Vaccine Against COVID-19

5 February 2021

GSK and CureVac start development immediately and plan vaccine availability in 2022

Preliminary Phase 3 Trial Results of the Russian COVID-19 Vaccine Sputnik V

04 February 2021

Interim results show that the vaccine is 91.6 % effective against COVID-19

How Long Does COVID-19 Immunity Last?

27 January 2021

Certain immune responses shown to last at least six months

How Innate Immunity Influences COVID-19 Viral Load

23 January 2021

Mathematical model of SARS-CoV-2 infection dynamics developed

Single-Dose COVID-19 Vaccine Works in Mice

16 January 2021

Self-assembling ferritin nanoparticles functionalized with SARS-CoV-2 spikes

Oxford University & AstraZeneka vaccine

A Third COVID-19 Vaccine Looks Very Promising

24 November 2020

AstraZeneca publishes preliminary analysis data from Phase III study

Another Coronavirus Vaccine Candidate Highly Effective

16 November 2020

Phase 3 study of Moderna's vaccine candidate met statistical criteria with 94.5 % efficacy

Vaccine Candidate More Than 90% Effective in Preventing COVID-19

10 November 2020

Pfizer and BioNTech announce vaccine candidate achieved success in first interim analysis from Phase 3 study

Potent Nanoparticle Vaccine against COVID-19 Designed

05 November 2020

Vaccine candidate produces high levels of virus-neutralizing antibodies in mice

EU Authorities Started Evaluating Data on COVID-19 Vaccines

EU Authorities Started Evaluating Data on COVID-19 Vaccines

07 October 2020

European Medicines Agency (EMA) starts the first rolling reviews of two COVID-19 vaccines in the EU

Herd Immunity Effects on COVID-19 in Hard-Hit Brazilian City

27 September 2020

Population immunity might have played a significant role in determining the size of the epidemic in Manaus

European Union Negotiates with Vaccine Producers

26 August 2020

European Commission expands talks with a fifth vaccine manufacturer

Clever Picture
Searching for a Vaccine

4 August 2020

Picture describes what happens during vaccination and gives a snapshot of which Covid-19 vaccine candidates are in which clinical phases

Pfizer and BioNTech Agree Vaccine Supply with the UK

22 July 2020

30 million doses of mRNA-based vaccine candidate against SARS-CoV-2 expected to be delivered in 2020/2021, subject to regulatory approval or authorization

Preparations for a Covid-19 Vaccine

15 April 2020

Merck supports the Jenner Institute to scale up manufacturing of Covid-19 vaccine candidate





Drugs and Treatments

Membrane-Based ACE2-Rich Nanoparticles against COVID-19

23 March 2021

Cells with high levels of ACE2 receptors used to create SARS-CoV-2 infection blockers

Oral Drug Blocks SARS-CoV-2 Transmission in Ferrets

09 December 2020

Repurposed ribonucleoside analogue inhibitor of influenza viruses

High-Yielding Synthesis of Antiviral Drug Candidate

19 November 2020

Improved preparation of EIDD-2801, currently in clinical trials for COVID-19 treatment

Nanoparticle Decoys Against COVID-19

Nanoparticle Decoys Against COVID-19

11 October 2020

Nanodecoys adsorb viruses and inflammatory cytokines

Targeting Coronavirus Protease Could Have Dual Effect

7 August 2020

Inhibitors of papain-like protease may block SARS-CoV-2 spread and promote immunity

Nucleotide Analogues Could Stop SARS-CoV-2 Replication

10 July 2020

Several compounds that shut down the virus's polymerase reaction were identified

First COVID-19 Treatment Authorized for the EU

6 July 2020

European Commission Grants Gilead Conditional Marketing Authorization for Veklury® (remdesivir) for the Treatment of COVID-19

Cellular Nanosponges Could Neutralize SARS-CoV-2

25 June 2020

Membranes derived from human cells act as an alternative target for the virus

Human Antibodies Protect against COVID-19 in Animal Study

20 June 2020

Potent neutralizing antibodies found in the blood of recovered patients

Continuous Flow Process for Remdesivir Synthesis

16 June 2020

Improved cyanation reaction as a key step for large-scale synthesis

New Antiviral Drug Candidates Targeting SARS-CoV-2 Main Protease

24 April 2020

Promising inhibitors with high activity and low toxicity

Structure of SARS-CoV-2 Main Protease as a Basis for Drug Design
21 March 2020
X-ray structures of promising target lead to improved drug candidate

α-Ketoamides Keep Different Viruses from Multiplying
4 March 2020
New broad-spectrum antivirals against coronaviruses and enteroviruses

Antiviral Drug Shows Promise Against MERS Coronavirus
20 February 2020
The broad-acting drug remdesivir could also be useful against the current coronavirus disease (COVID-19)

Suggesting Potential Drug Candidates for Coronavirus
5 February 2020
Summarizing the current research and suggesting potential drug candidates for treating patients suffering from the 2019-nCoV acute respiratory disease

 

  • LitCovid
    Curated literature hub for tracking up-to-date scientific information about COVID-19
  • Many publishers and other entities have signed a joint statement to ensure that COVID-19 research findings and data are shared rapidly and openly. Free articles related to the coronavirus from Cambridge University Press, ElsevierOxford University Press, Springer Nature, Wiley.
  • Wiley is providing free access to online learning solutions. Instructors without an adopted online learning solution, such as WileyPLUS, Knewton Alta, or zyBooks, can receive free access for their students for the remainder of the Spring 2020 term.
  • What Publishers Are Doing To Help During The Coronavirus Pandemic, Association of American Publishers

 

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