SARS-CoV-2 Virus

  • Author: ChemViews Magazine
  • Published Date: 26 March 2020
  • Copyright: Wiley-VCH Verlag GmbH & Co. KGaA
thumbnail image: SARS-CoV-2 Virus

What We Know About the Coronavirus

The coronavirus SARS-CoV-2 causes the current outbreak of the respiratory disease COVID-19. The virus was first detected in Wuhan, China, in December 2019 and has spread globally by now. The Center for Systems Science and Engineering (CSSE) at Johns Hopkins University, Baltimore, MD, USA, provides current updates of coronavirus COVID-19 global cases. The World Health Organization (WHO), which declared the rapidly spreading coronavirus outbreak a pandemic, describes how to protect yourself.

Below, you will find articles that have appeared on ChemistryViews covering the following topics:




Virus Transmission and Protective Measures

Copper Nanowire Foams for Reusable Air Filters

03 April 2021

Possible face mask material provides high particulate filtration performance and is easy to clean, reuse, and recycle

What Can Stores Do to Prevent COVID-19 Transmission?

03 March 2021

One-way aisles prevent transmission by close contact; other measures are needed to avoid exposure to aerosols

Aerosol Transmission in Cruise-Ship COVID-19 Outbreak

19 February 2021

Scenarios based on the Diamond Princess outbreak show the importance of airborne transmission

Simulation Shows How SARS-CoV-2 Moves through a Restaurant

12 February 2021

Detailed investigation of known outbreak shows roles of ventilation and air conditioning

How Innate Immunity Influences COVID-19 Viral Load

23 January 2021

Mathematical model of SARS-CoV-2 infection dynamics developed

What Makes Some Groups More Vulnerable to COVID-19?

11 December 2020

SARS-CoV-2 infectivity might depend on the host's redox status

Spread and Mutations of SARS-CoV-2 in Austria Analyzed

25 November 2020

National-scale analysis of COVID-19 superspreading during the first wave of infections in the spring

Cloth Face Masks that Disinfect Themselves in Sunlight

21 November 2020

Functionalized cotton fabrics produce reactive oxygen species (ROS) under light exposure

How COVID-19 Spreads in Meat Processing Plants

08 November 2020

Investigation of outbreak at German meat processing plant shows important factors for virus spread

Heated Face Mask Could Inactivate SARS-CoV-2

Heated Face Mask Could Inactivate SARS-CoV-2

01 November 2020

Researchers aim to build masks with a heated copper mesh

New Model for Droplet Physics Could Inform COVID-19 Guidelines

New Model for Droplet Physics Could Inform COVID-19 Guidelines

29 October 2020

Masks and distancing are helpful, but might not be enough to prevent all contact with the virus

How Far Can Speech-Induced Airflow Carry Viruses?

29 September 2020

Plosive sounds like "p" form air puffs that can transport aerosols over 2 m in 30 s

Simple Method to Test the Efficacy of Face Masks

12 August 2020

Fast, low-cost estimation of droplet retention by different types of masks

How Well Do Face Masks Stop Droplets?

4 July 2020

Simple visualization experiments show effects of mask fit, materials, and layers

Replaceable Filter Membrane for More Efficient Face Masks

26 May 2020

Nanoporous hydrophobic polymer membrane developed

Unrecognized Infection Could Play Mayor Role in Spread of COVID-19
18 March 2020
Model that includes undocumented cases explains rapid growth in the number of infections

How Long Can the SARS-CoV-2 Virus Live on Surfaces and in Aerosols?
14 March 2020
New results on the stability of the virus causing COVID-19

Clever Picture
Coronavirus Entering and Replicating in a Host Cell
3 March 2020
https://doi.org/10.1002/chemv.202000018
Where the coronavirus comes from and how it infects the human body

How Long Can Coronaviruses Live on Surfaces?
13 February 2020
Literature review finds coronaviruses could persist on hard surfaces for up to nine days, but can be killed with the right disinfectant





Vaccines and Immunity

Simple Indicator Ensures Ultracold Supply Chain for mRNA Vaccines

04 April 2021

Alerting health care workers to unsafe temperatures during transport

Single Shot of COVID-19 Vaccine Boosts Antibodies in Recovered Patients

27 March 2021

Vaccinating previously infected persons could improve protection against multiple virus variants

First Single-Shot COVID-19 Vaccine

First Single-Shot COVID-19 Vaccine

02 March 2021

Johnson & Johnson's vaccine receives emergency approval from U.S. FDA

Lipid Production for mRNA-Based Vaccines in Germany

16 February 2021

Evonik is investing in the production of lipids at its Hanau and Dossenheim sites

New BioNTech Plant in Marburg, Germany

10 February 2021

This new BioNTech site will become one of the largest mRNA manufacturing sites in Europe

Next-Generation mRNA Vaccine Against COVID-19

Next-Generation mRNA Vaccine Against COVID-19

5 February 2021

GSK and CureVac start development immediately and plan vaccine availability in 2022

Preliminary Phase 3 Trial Results of the Russian COVID-19 Vaccine Sputnik V

04 February 2021

Interim results show that the vaccine is 91.6 % effective against COVID-19

How Long Does COVID-19 Immunity Last?

27 January 2021

Certain immune responses shown to last at least six months

How Innate Immunity Influences COVID-19 Viral Load

23 January 2021

Mathematical model of SARS-CoV-2 infection dynamics developed

Single-Dose COVID-19 Vaccine Works in Mice

16 January 2021

Self-assembling ferritin nanoparticles functionalized with SARS-CoV-2 spikes

Oxford University & AstraZeneka vaccine

A Third COVID-19 Vaccine Looks Very Promising

24 November 2020

AstraZeneca publishes preliminary analysis data from Phase III study

Another Coronavirus Vaccine Candidate Highly Effective

16 November 2020

Phase 3 study of Moderna's vaccine candidate met statistical criteria with 94.5 % efficacy

Vaccine Candidate More Than 90% Effective in Preventing COVID-19

10 November 2020

Pfizer and BioNTech announce vaccine candidate achieved success in first interim analysis from Phase 3 study

Potent Nanoparticle Vaccine against COVID-19 Designed

05 November 2020

Vaccine candidate produces high levels of virus-neutralizing antibodies in mice

EU Authorities Started Evaluating Data on COVID-19 Vaccines

EU Authorities Started Evaluating Data on COVID-19 Vaccines

07 October 2020

European Medicines Agency (EMA) starts the first rolling reviews of two COVID-19 vaccines in the EU

Herd Immunity Effects on COVID-19 in Hard-Hit Brazilian City

27 September 2020

Population immunity might have played a significant role in determining the size of the epidemic in Manaus

European Union Negotiates with Vaccine Producers

26 August 2020

European Commission expands talks with a fifth vaccine manufacturer

Clever Picture
Searching for a Vaccine

4 August 2020

Picture describes what happens during vaccination and gives a snapshot of which Covid-19 vaccine candidates are in which clinical phases

Pfizer and BioNTech Agree Vaccine Supply with the UK

22 July 2020

30 million doses of mRNA-based vaccine candidate against SARS-CoV-2 expected to be delivered in 2020/2021, subject to regulatory approval or authorization

Preparations for a Covid-19 Vaccine

15 April 2020

Merck supports the Jenner Institute to scale up manufacturing of Covid-19 vaccine candidate





Drugs and Treatments

Membrane-Based ACE2-Rich Nanoparticles against COVID-19

23 March 2021

Cells with high levels of ACE2 receptors used to create SARS-CoV-2 infection blockers

Oral Drug Blocks SARS-CoV-2 Transmission in Ferrets

09 December 2020

Repurposed ribonucleoside analogue inhibitor of influenza viruses

High-Yielding Synthesis of Antiviral Drug Candidate

19 November 2020

Improved preparation of EIDD-2801, currently in clinical trials for COVID-19 treatment

Nanoparticle Decoys Against COVID-19

Nanoparticle Decoys Against COVID-19

11 October 2020

Nanodecoys adsorb viruses and inflammatory cytokines

Targeting Coronavirus Protease Could Have Dual Effect

7 August 2020

Inhibitors of papain-like protease may block SARS-CoV-2 spread and promote immunity

Nucleotide Analogues Could Stop SARS-CoV-2 Replication

10 July 2020

Several compounds that shut down the virus's polymerase reaction were identified

First COVID-19 Treatment Authorized for the EU

6 July 2020

European Commission Grants Gilead Conditional Marketing Authorization for Veklury® (remdesivir) for the Treatment of COVID-19

Cellular Nanosponges Could Neutralize SARS-CoV-2

25 June 2020

Membranes derived from human cells act as an alternative target for the virus

Human Antibodies Protect against COVID-19 in Animal Study

20 June 2020

Potent neutralizing antibodies found in the blood of recovered patients

Continuous Flow Process for Remdesivir Synthesis

16 June 2020

Improved cyanation reaction as a key step for large-scale synthesis

New Antiviral Drug Candidates Targeting SARS-CoV-2 Main Protease

24 April 2020

Promising inhibitors with high activity and low toxicity

Structure of SARS-CoV-2 Main Protease as a Basis for Drug Design
21 March 2020
X-ray structures of promising target lead to improved drug candidate

α-Ketoamides Keep Different Viruses from Multiplying
4 March 2020
New broad-spectrum antivirals against coronaviruses and enteroviruses

Antiviral Drug Shows Promise Against MERS Coronavirus
20 February 2020
The broad-acting drug remdesivir could also be useful against the current coronavirus disease (COVID-19)

Suggesting Potential Drug Candidates for Coronavirus
5 February 2020
Summarizing the current research and suggesting potential drug candidates for treating patients suffering from the 2019-nCoV acute respiratory disease





Testing

Nanofiber Swabs Could Improve Sensitivity of COVID-19 Tests

31 January 2021

Improved sample collection reduces false negative rate

Pooling Method for High-Throughput COVID-19 Tests

27 August 2020

Increase in testing efficiency leads to higher overall capacity and lower costs

Proof-of-Concept for Faster COVID-19 Test

18 April 2020

Gold nanoislands with DNA receptors used for the detection of SARS-CoV-2

Clever Picture
COVID-19 Specific Testing

7 April 2020

Picture describes how coronavirus testing work

Rapid, Sensitive Test for COVID-19 Developed
22 March 2020
New method over three times faster than previous approaches





Virus Structure and Receptors

SARS-CoV-2-Infected Cells Imaged Using Helium Ion Microscopy

6 February 2021

Areas of interaction between cells and virus particles studied

Structure of a Key Coronavirus Protein Determined

14 November 2020

The envelope protein E acts as an ion channel and could be a target for drugs against the SARS-CoV-2 virus

Stabilized Versions of the SARS-CoV-2 Spike Protein

30 July 2020

Improved protein yields and stability could be useful for the development of vaccines and treatments

How SARS-CoV-2 Copies Its Genetic Information

7 May 2020

Structure of replicating coronavirus polymerase solved

Cells in the Nose Could Act as Entry Points for SARS-CoV-2

30 April 2020

Study of the expression of the ACE2 receptor, which allows cellular entry of the virus

Structure of SARS-CoV-2 Main Protease as a Basis for Drug Design
21 March 2020
X-ray structures of promising target lead to improved drug candidate

Structure of Coronavirus Receptor on Human Cells Determined
6 March 2020
Cryo-EM structures of full-length human angiotensin-converting enzyme 2 (ACE2)

Structure of "Spike" Protein in New Coronavirus Determined
21 February 2020
Results could help to develop a vaccine and antibody treatments





Other Topics

Studying in the Coronavirus Pandemic

15 February 2021

In the midst of the lockdown, chemistry students talk about their daily study routine

Does Climate Change Contribute to New Bat-Borne Coronaviruses?

14 February 2021

Higher bat diversity leads to higher numbers of coronaviruses locally—likely contributing to both SARS and COVID-19 outbreaks

Neanderthal Genes Associated with Higher Risk of Severe COVID-19

Neanderthal Genes Associated with Higher Risk of Severe COVID-19

09 October 2020

Genomic variants inherited from Neanderthals most commonly found in South Asians and Europeans today

The Pandemic Does Not Affect All Researchers Equally

23 July 2020

Scientists with young children, female researchers, and "bench scientists" report the largest declines in research time

Commentary
A MIDLOCKDOWN NIGHT’S DREAM That Is a Saving Redox Reaction

07 July 2020

2nd Italian Chemical Society’s literary contest gives voice to the young generation during COVID-19

Commentary
BE LIKE CEZANNE – Upset Paris With an Apple

07 July 2020

2nd Italian Chemical Society’s literary contest gives voice to the young generation during COVID-19

Commentary
THAT’S CHEMISTRY... BABY!

06 July 2020

2nd Italian Chemical Society’s literary contest gives voice to the young generation during COVID-19


Special Science Communication Prize for Virologist Christian Drosten

4 May 2020

Clear, fact-based science communication in the COVID-19 pandemic to the public honored

Spotlight
Experiences of Two Researchers in the COVID-19 Crisis

7 April 2020

Gianluca Giorgi, Italy, and Stefanie Dehnen, Germany, give personal insights into this challenging situation

How to Use Your Computer to Help with Coronavirus Research
1 April 2020
Projects use crowd sourcing and donated computing power for drug discovery

Engineered Cell Line for Coronavirus Isolation
16 March 2020
Modified cell line is highly susceptible to SARS-CoV-2 infection, which makes it useful for studying the virus

Clever Picture
Coronavirus Entering and Replicating in a Host Cell
3 March 2020
https://doi.org/10.1002/chemv.202000018
Where the coronavirus comes from and how it infects the human body

 

  • LitCovid
    Curated literature hub for tracking up-to-date scientific information about COVID-19
  • Many publishers and other entities have signed a joint statement to ensure that COVID-19 research findings and data are shared rapidly and openly. Free articles related to the coronavirus from Cambridge University Press, ElsevierOxford University Press, Springer Nature, Wiley.
  • Wiley is providing free access to online learning solutions. Instructors without an adopted online learning solution, such as WileyPLUS, Knewton Alta, or zyBooks, can receive free access for their students for the remainder of the Spring 2020 term.
  • What Publishers Are Doing To Help During The Coronavirus Pandemic, Association of American Publishers

 

 

 

 

Article Views: 12685

Sign in Area

Please sign in below

Additional Sign In options

Please note that to comment on an article you must be registered and logged in.
Registration is for free, you may already be registered to receive, e.g., the newsletter. When you register on this website, please ensure you view our terms and conditions. All comments are subject to moderation.

Article Comments - To add a comment please sign in

If you would like to reuse any content, in print or online, from ChemistryViews.org, please contact us first for permission. more

Follow on Facebook Follow on Twitter Follow on YouTube Follow on LinkedIn Follow on Instagram RSS Sign up for newsletters

Magazine of Chemistry Europe (16 European Chemical Societies) published by Wiley-VCH